Lymphocytes are mononucleate, nongranular leukocytes of lymphoid tissue, participating in immunity. They are found in blood, lymph and lymphoid  tissues such as spleen, lymph nodes, tonsils, Peyer’s patches, appendix. etc. 
The lymphocytes are of two types. They are B lymphocytes and T lymphocytes.

Comparison of B and T cells  (B cell vs T cell)
B cells
T cells
Origin : Bone marrow in adults
Origin :Bone marrow in adults
Maturation : Lymphoid tissue or bone marrow; Bursa of Fabricius in birds
Maturation: Thymus
Longevity : Short (Few days to a week)
Longevity :Long (Months to years)
Complement receptors : Present
Complement receptors: Absent
Surface immunoglobulins :Present
Surface immunoglobulins :Absent
Proliferation : Proliferate upon antigenic stimulation, differentiate into plasma and memory cells
Proliferation : Proliferate upon antigenic stimulation
Type of immunity :  Humoral immunity
Type of immunity ;Cell mediated and humoral
Secretary product :Antibodies
Secretary product : Lymphokines
Distribution :
High in spleen, lymph nodes, bone marrow and other lymphoid tissues, Low in blood
High in blood, lymph and lymphoid tissue
Types and Functions

  • Memory cells- along lived cell responsible for the anamnestic response.
  • Plasma cell- a cell arising from a B cell that manufactures specific antibodies

Types and Functions

  • Tc Cell- Lysis cells recognized as non self and parasite infected cells.
  • TH cell- It is necessary for B cell activation by T-dependent antigens and T effector cell.
  • T regulator cell- It develops into TH or Ts cells and control balance between enhancement and suppression of response to antigen.
  • Ts cell: It blocks induction  and or/ activation of TH cells and B cells. It helps maintain tolerance.
  • TD TH cell: It provides protection against infectious agents, mediates inflammation and activates macrophages in delayed type hypersensitivity
  • Null cells- Lymphocytes that lacks surface cell markers.


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  1. This piece of information is highly useful to students of Animal physiology. Physical and chemical properties of blood in arteries and veins will be also useful In case you give please.


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