Chromosomal disorders: These genetic disorders are caused due to absence or excess or abnormal arrangement of one or more chromosomes. These are noninheritable and pedigree analysis of a family does not help in tracing the pattern of inheritance of such chromosomal disorders. These are two types: abnormalities due to aneuploidy and aberrations either in autosomes or in sex chromosomes.
Autosomal vs Sex chromosomal disorders
Autosomal disorders:1. These arise by gene mutations in autosomal chromosomes.
2. These disorders affect both the sexes, i.e., males and females.
3. The mutated gene may be dominant / recessive.
4. The suffer is homozygous or heterozygous, e.g., Down’s syndrome, Huntington's disease’s chorea, sickle cell anemia, alkaptonuria.
Sex chromosomal disorders:
1. These arise by gene mutation in sex chromosomes (mostly X chromosomes.
2. These disorders affect the males more than the females.
3. The mutated gene is recessive.
4. The sufferer is hemizygous, e.g.,Klinefelter’s syndrome,Turner’s syndrome, super female, haemophilia, muscular dystrophy.
A call girl or female escort is a sex worker who (unlike a street walker) does not display her profession to the general public; nor does she usually work in an institution like a brothel, although she may be employed by an escort agency. Escorts in Islamabad
ReplyDeleteThere is a surprising variety of sex toys from purely male or purely female sex toys to toys that can be used by both sexes. Some sex toys can also be classified as sex aids or marital aids. This article outlines what is available. indian webcam chat
ReplyDelete